Former CBU student Preston MacQueen will present his research on “The Pursuit of Effective Catalysis for C-C and C-N Cross-Coupling under Mild Conditions” on July 4th at 12:00pm in CE-265. Dr. MacQueen has completed his PhD under Dr. Mark Stradiotto at Dalhousie University, and will begin his postdoctoral studies in the fall at MIT with Dr. Tim Jamison in flow chemistry. He has accepted a two month research position in Dr. Stephanie MacQuarrie’s lab at Cape Breton University for the summer.
All welcome. Light refreshments will be provided.
The Pursuit of Effective Catalysis for C-C and C-N Cross-Coupling under Mild Conditions
The selective mono-arylation of small molecules, a class of reactions predominantly achieved via transition metal-catalyzed cross-coupling reactions, is an important transformation for converting commercially available, abundant materials into value added products. Major advancements have been made with palladium-catalysis in mono-arylation reactions with such abundant stock materials as acetone and ammonia as well as other related compounds. These arylated amines and ketones are widely used in the synthesis of pharmaceuticals, agrochemicals and other fine chemicals. Notwithstanding the utility of palladium in these challenging transformations, it has become desirable to move towards more cost efficient and abundant metals for catalysis. Nickel is significantly less expensive than palladium and shows the potential to provide similar or superior reactivity