Friday, March 3, 2017, from 11:30 a.m.- 12:30 p.m., CS104 (Verschuren Centre Theatre)
Further Progress in Biotin Chemistry.
Dr. Andrew Grant is Professor in the Department of Chemistry at Mount Allison University
We have been interested in understanding how the enzyme cofactor biotin operates in the enzyme acetyl-CoA carboxylase. Twisted biotin analogues A & B were designed to probe whether the sulfur in ring B participates in the chemistry. This talk will describe our recent efforts towards the synthesis of A & B.